名称：WWOX (Phospho-Tyr33)

别名：FOR; WOX1; Aberrant WW domain-containing oxidoreductase;

Pathway：Wnt signaling pathway

Modified：Phosphorylated

Targets：Disease

描述

WW domain-containing proteins are found in all eukaryotes and play an important role in the regulation of a wide variety of cellular functions such as protein degradation, transcription, and RNA splicing. This gene encodes a protein which contains 2 WW domains and a short-chain dehydrogenase/reductase domain (SRD). The highest normal expression of this gene is detected in hormonally regulated tissues such as testis, ovary, and prostate. This expression pattern and the presence of an SRD domain suggest a role for this gene in steroid metabolism. Bednarek A.K., Cancer Res. 60:2140-2145(2000)Ried K., Hum. Mol. Genet. 9:1651-1663(2000)Bednarek A.K., Cancer Res. 61:8068-8073(2001).

Specification

Entrez GeneID：51741;

Swissprot：Q9NZC7

Gene Accession：Swiss-Prot#: Q96KM3; NCBI Gene#: 51741; NCBI Protein#: NP_057457.1.

WB Predicted band size：55kDa

Host/Isotype：Rabbit IgG

Antibody Type：Primary antibody

Storage：Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Species Reactivity：Human

免疫原：Peptide sequence around phosphorylation site of tyrosine 33 (W-V-Y(p)-Y-A) derived from Human WWOX.

Formulation：Purified antibody in PBS with 0.05% sodium azide.

Application

Application：WB,IHC

WB：1/500-1/1000

IHC：1/50-1/100

宿主：Rabbit