名称：LEF1

别名：LEF1; Lymphoid enhancer-binding factor 1; LEF-1; T cell-specific transcription factor 1-alpha; TCF1-alpha

Pathway：Wnt signaling pathway

Pathway：Hippo signaling pathway

描述

Participates in the Wnt signaling pathway. Activates transcription of target genes in the presence of CTNNB1 and EP300. May play a role in hair cell differentiation and follicle morphogenesis. TLE1, TLE2, TLE3 and TLE4 repress transactivation mediated by LEF1 and CTNNB1. Regulates T-cell receptor alpha enhancer function. Binds DNA in a sequence-specific manner. PIAG antagonizes both Wnt-dependent and Wnt-independent activation by LEF1 (By similarity).

Specification

Entrez GeneID：51176

Swissprot：Q9UJU2

WB Predicted band size：Calculated MW: 44 kDa; Observed MW: 25-58 kDa

Host/Isotype：Rabbit IgG

Antibody Type：Primary antibody

Storage：Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Species Reactivity：Human,Rat

免疫原：A synthetic peptide of human LEF1

Formulation：Purified antibody in TBS with 0.05% sodium azide,0.05%BSA and 50% glycerol.

Application

Application：WB,IP,IHC,IF,FCM

WB：1/500-1/1000

IP：1/10-1/20

IHC：1/50-1/100

ICC：1/50-1/200

FCM：1/50-1/100

宿主：Rabbit