名称：SMAC

别名：SMAC; DFNA64; DIABLO; SMAC3

Targets：Disease

描述

Smac/Diablo is a 21 kDa mammalian mitochondrial protein that functions as a regulatory component during apoptosis. Upon mitochondrial stress, Smac/Diablo is released from mitochondria and competes with caspases for binding of IAPs (inhibitor of apoptosis proteins). The interaction of Smac/Diablo with IAPs relieves the inhibitory effect of the IAPs on caspases.

Specification

Entrez GeneID：56616

Swissprot：Q9NR28

WB Predicted band size：Calculated MW: 27 kDa; Observed MW: 21 kDa

Host/Isotype：Rabbit IgG

Antibody Type：Primary antibody

Storage：Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Species Reactivity：Human,Mouse,Rat

免疫原：A synthesized peptide derived from human Smac/Diablo

Formulation：Purified antibody in PBS with 0.05% sodium azide.

Application

Application：WB,IP,IHC,IF,FCM

WB：1/500-1/1000

IP：1/10-1/20

IHC：1/50-1/100

ICC：1/50-1/200

FCM：1/50-1/100

宿主：Rabbit