名称：Phospho-SMAD4(T277)

别名：Mothers against decapentaplegic homolog 4, MAD homolog 4, Mothers against DPP homolog 4, Deletion target in pancreatic carcinoma 4, SMAD family member 4, SMAD 4, Smad4, hSMAD4, SMAD4, DPC4, MADH4

Pathway：TGF-beta signaling pathway

Modified：Phosphorylated

Targets：Disease

描述

Common mediator of signal transduction by TGF-beta (transforming growth factor) superfamily, SMAD4 is the common SMAD (co-SMAD). It promotes binding of the SMAD2/SMAD4/FAST-1 complex to DNA and provides an activation function required for SMAD1 or SMAD2 to stimulate transcription. It may act as a tumor suppressor.

Specification

Entrez GeneID：4089

Swissprot：Q13485

WB Predicted band size：60.4kDa

Host/Isotype：Rabbit IgG

Antibody Type：Primary antibody

Storage：Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Species Reactivity：Human, Mouse, Rat

免疫原：This SMAD4 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T277 of human SMAD4.

Formulation：Purified antibody in PBS with 0.05% sodium azide.

Application

Application：WB,IHC-P,IF

WB：DB: 1/500

IHC：1/100-1/500

ICC：1/10-1/50

宿主：Rabbit