名称：Axin 2

别名：Axil; Axin like protein; Axin2; Axis inhibition protein 2; Conductin

Pathway：Wnt signaling pathway

描述

Axin1 (Axis inhibition protein 1) and Axin2 are multidomain scaffold proteins that negatively regulate Wnt signaling. Axin1 interacts with APC, GSK-3β, Dvl, and β-catenin and promotes the GSK-3β-mediated phosphorylation and subsequent degradation of β-catenin .Down-regulates beta-catenin.

Specification

Entrez GeneID：8313

Swissprot：Q9Y2T1

WB Predicted band size：Calculated MW: 94 kDa; Observed MW: 94 kDa

Host/Isotype：Rabbit IgG

Antibody Type：Primary antibody

Storage：Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Species Reactivity：Human,Mouse,Rat

免疫原：A synthesized peptide derived from human Axin2

Formulation：Purified antibody in PBS with 0.05% sodium azide.

Application

Application：WB,IHC,IF

WB：1/500-1/1000

IHC：1/50-1/100

ICC：1/50-1/200

宿主：Rabbit