名称：FAK

别名：PTK2; FAK; FAK1; Focal adhesion kinase 1; FADK 1; Focal adhesion kinase-related nonkinase; FRNK; Protein phosphatase 1 regulatory subunit 71; PPP1R71; Protein-tyrosine kinase 2; p125FAK; pp125FAK

Pathway：PI3K-Akt signaling pathway

描述

This gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal transduction pathways triggered in response to certain neural peptides or to cell interactions with the extracellular matrix.

Specification

Entrez GeneID：5747

Swissprot：Q05397

WB Predicted band size：Calculated MW: 119 kDa; Observed MW: 119 kDa

Host/Isotype：Rabbit IgG

Antibody Type：Primary antibody

Storage：Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Species Reactivity：Human,Mouse,Rat

免疫原：A synthesized peptide derived from human FAK

Formulation：Purified antibody in PBS with 0.05% sodium azide.

Application

Application：WB,IP,IHC,IF,FCM

WB：1/500-1/1000

IP：1/10-1/20

IHC：1/50-1/100

ICC：1/50-1/200

FCM：1/50-1/100

宿主：Rabbit