名称：Fas

别名：FAS; ALPS1A; APO-1; APT1; CD95; FAS1; FASTM; TNFRSF6

Pathway：MAPK signaling pathway

Targets：Disease

描述

Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis.

Specification

Entrez GeneID：355

Swissprot：P25445

WB Predicted band size：Calculated MW: 38 kDa; Observed MW: 48 kDa

Host/Isotype：Rabbit IgG

Antibody Type：Primary antibody

Storage：Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Species Reactivity：Human

免疫原：A synthesized peptide derived from human Fas

Formulation：Purified antibody in PBS with 0.05% sodium azide.

Application

Application：WB,IHC,IF,FCM

WB：1/500-1/1000

IHC：1/50-1/100

ICC：1/50-1/200

FCM：1/50-1/100

宿主：Rabbit