名称：OTC

别名：OTCase; Ornithine carbamoyltransferase; mitochondrial; OCTD

Targets：Disease

描述

This nuclear gene encodes a mitochondrial matrix enzyme. Missense, nonsense, and frameshift mutations in this enzyme lead to ornithine transcarbamylase deficiency, which causes hyperammonemia. Since the gene for this enzyme maps close to that for Duchenne muscular dystrophy, it may play a role in that disease also.

Specification

Entrez GeneID：5009

Swissprot：P00480

WB Predicted band size：Calculated MW: 40 kDa; Observed MW: 40 kDa

Host/Isotype：Rabbit IgG

Antibody Type：Primary antibody

Storage：Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Species Reactivity：Mouse,Rat

免疫原：A synthetic peptide of human Ornithine Carbamoyltransferase

Formulation：Purified antibody in TBS with 0.05% sodium azide,0.05%BSA and 50% glycerol.

Application

Application：WB,IP,IHC

WB：1/500-1/1000

IP：1/10-1/20

IHC：1/50-1/100

宿主：Rabbit