ProMab P22278 Rabbit Monoclonal Antibody to BUBR1
- 销售价:
- ¥1280.00
- 市场价:
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¥1280.00 - 编号:
- 202602121099080
- 货号:
- P22278-50ul
-
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商品介绍
名称:BUBR1
别名:BUB1B; BUBR1; MAD3L; SSK1; Mitotic checkpoint serine/threonine-protein kinase BUB1 beta; MAD3/BUB1-related protein kinase; hBUBR1; Mitotic checkpoint kinase MAD3L; Protein SSK1
Targets:Disease
描述Essential component of the mitotic checkpoint. Required for normal mitosis progression. The mitotic checkpoint delays anaphase until all chromosomes are properly attached to the mitotic spindle. One of its checkpoint functions is to inhibit the activity of the anaphase-promoting complex/cyclosome (APC/C) by blocking the binding of CDC20 to APC/C, independently of its kinase activity. The other is to monitor kinetochore activities that depend on the kinetochore motor CENPE. Required for kinetochore localization of CENPE.
Specification
Entrez GeneID:701
Swissprot:O60566
WB Predicted band size:Calculated MW: 120 kDa; Observed MW: 120 kDa
Host/Isotype:Rabbit IgG
Antibody Type:Primary antibody
Storage:Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity:Human,Hamster
免疫原:A synthetic peptide of human BubR1
Formulation:Purified antibody in TBS with 0.05% sodium azide,0.05%BSA and 50% glycerol.
Application
Application:WB,IP,IHC
WB:1/500-1/1000
IP:1/10-1/20
IHC:1/50-1/100
宿主:Rabbit
商品参数
| 商品介绍 | |
|---|---|
| 单位 | 支 |
| 品牌 | ProMab/远泰 |
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