名称：Paxillin

别名：PXN; Paxillin

描述

Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). PXN is a multi-domain cytoskeletal protein that localizes primarily to focal adhesion sites to the extracellular matrix. Phosphorylated by focal adhesion kinase (FAK) and is a component of integrin signaling. Its phosphorylation provides docking sites for recruitment of signaling molecules to focal adhesions.

Specification

Entrez GeneID：5829

Swissprot：P49023

WB Predicted band size：Calculated MW: 65 kDa; Observed MW: 65 kDa

Host/Isotype：Rabbit IgG

Antibody Type：Primary antibody

Storage：Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Species Reactivity：Human,Rat,Hamster

免疫原：A synthetic peptide of human Paxillin

Formulation：Purified antibody in TBS with 0.05% sodium azide,0.05%BSA and 50% glycerol.

Application

Application：WB,IP,IHC

WB：1/500-1/1000

IP：1/10-1/20

IHC：1/50-1/100

宿主：Rabbit