名称：GRK2

别名：GRK2; BARK1; FLJ16718; BETA-ARK1; ADRBK1

描述

GRK2 kinase activity and cellular localization are tightly regulated by interactions with activated receptors, G-beta and G-gamma subunits, adaptor proteins, phospholipids, caveolin and calmodulin, as well as by phosphorylation. PKC phosphorylation enhances GRK2 activity by promoting its membrane localization and by abolishing the inhibitory association of calmodulin.

Specification

Entrez GeneID：156

Swissprot：P25098

WB Predicted band size：Calculated MW: 80 kDa; Observed MW: 80 kDa

Host/Isotype：Rabbit IgG

Antibody Type：Primary antibody

Storage：Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Species Reactivity：Human

免疫原：A synthetic peptide of human GRK2

Formulation：Purified antibody in TBS with 0.05% sodium azide,0.05%BSA and 50% glycerol.

Application

Application：WB,IP

WB：1/500-1/1000

IP：1/10-1/20

宿主：Rabbit