名称：PAK1

别名：PAK1; Serine/threonine-protein kinase PAK 1; Alpha-PAK; p21-activated kinase 1; PAK-1; p65-PAK

Pathway：MAPK signaling pathway

Targets：Disease

描述

The activated kinase acts on a variety of targets. Likely to be the GTPase effector that links the Rho-related GTPases to the JNK MAP kinase pathway. Activated by CDC42 and RAC1. Involved in dissolution of stress fibers and reorganization of focal complexes. Involved in regulation of microtubule biogenesis through phosphorylation of TBCB.

Specification

Entrez GeneID：5058

Swissprot：Q13153

WB Predicted band size：Calculated MW: 61 kDa; Observed MW: 61 kDa

Host/Isotype：Rabbit IgG

Antibody Type：Primary antibody

Storage：Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Species Reactivity：Human,Mouse,Rat,Hamster

免疫原：A synthetic peptide of human PAK1

Formulation：Purified antibody in TBS with 0.05% sodium azide,0.05%BSA and 50% glycerol.

Application

Application：WB,IP,IHC,IF

WB：1/500-1/1000

IP：1/10-1/20

IHC：1/50-1/100

ICC：1/50-1/200

宿主：Rabbit