名称：RAIDD

别名：CRADD; MGC9163; RAIDD; Death adaptor molecule RAIDD; Death domain containing protein CRADD

Targets：Disease

描述

The receptor interacting protein RIP is a death domain-containing serine/threonine kinase which associates with FAS or the TNF-R1 binding protein TRADD. RAIDD (RIP-associated ICH-1/Ced-3 homologous protein with a death domain) has been identified as a RIP binding protein that also associates with members of the caspase family, providing a link between activation of the TNF-Rs and the triggering of the cysteine protease cascade. The amino-terminal domain of RAIDD shares significant homology with the prodomain of ICH-1 and mediates the binding of RAIDD to this cysteine protease.

Specification

Entrez GeneID：8738

Swissprot：P78560

WB Predicted band size：Calculated MW: 23 kDa; Observed MW: 23 kDa

Host/Isotype：Rabbit IgG

Antibody Type：Primary antibody

Storage：Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Species Reactivity：Human

免疫原：A synthetic peptide of human RAIDD

Formulation：Purified antibody in TBS with 0.05% sodium azide,0.05%BSA and 50% glycerol.

Application

Application：WB,IP,IF

WB：1/500-1/1000

IP：1/10-1/20

ICC：1/50-1/200

宿主：Rabbit