名称：beta Catenin

别名：CTNNB1; CTNNB; OK/SW-cl.35; Catenin beta-1; Beta-catenin

Pathway：Wnt signaling pathway

Pathway：Hippo signaling pathway

Targets：Disease

描述

Beta-catenin is an adherens junction protein. Adherens junctions (AJs; also called the zonula adherens) are critical for the establishment and maintenance of epithelial layers, such as those lining organ surfaces. AJs mediate adhesion between cells, communicate a signal that neighboring cells are present, and anchor the actin cytoskeleton. In serving these roles, AJs regulate normal cell growth and behavior.

Specification

Entrez GeneID：1499

Swissprot：P35222

WB Predicted band size：Calculated MW: 85 kDa; Observed MW: 85 kDa

Host/Isotype：Rabbit IgG

Antibody Type：Primary antibody

Storage：Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Species Reactivity：Human,Mouse,Rat,Hamster

免疫原：A synthetic peptide of human beta Catenin

Formulation：Purified antibody in TBS with 0.05% sodium azide,0.05%BSA and 50% glycerol.

Application

Application：WB,IP,IHC

WB：1/500-1/1000

IP：1/10-1/20

IHC：1/50-1/100

宿主：Rabbit