名称：Notch4

别名：NOTCH4; INT3; Neurogenic locus notch homolog protein 4; Notch 4; hNotch4

Pathway：Notch signaling pathway

描述

Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs. May regulate branching morphogenesis in the developing vascular system (By similarity).

Specification

Entrez GeneID：4855

Swissprot：Q99466

WB Predicted band size：Calculated MW: 210 kDa; Observed MW: 36 kDa

Host/Isotype：Rabbit IgG

Antibody Type：Primary antibody

Storage：Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Species Reactivity：Human

免疫原：A synthetic peptide of human NOTCH4

Formulation：Purified antibody in TBS with 0.05% sodium azide,0.05%BSA and 50% glycerol.

Application

Application：WB

WB：1/500-1/1000

宿主：Rabbit