擎科科邦邦商城

ProMab P22150 Rabbit Monoclonal Antibody to UFD1

销售价:
¥1280.00
市场价:
¥1280.00
编号:
202602121098503
货号:
P22150-50ul
累计评价

暂无评价

  • 月销量: 0
  • 评分数: 0
  • 评分: 0.0
产品规格:
100ul 50ul
数量:

商品介绍

名称:UFD1

别名:UFD1L

描述

Essential component of the ubiquitin-dependent proteolytic pathway which degrades ubiquitin fusion proteins. The ternary complex containing UFD1, VCP and NPLOC4 binds ubiquitinated proteins and is necessary for the export of misfolded proteins from the ER to the cytoplasm, where they are degraded by the proteasome. The NPLOC4-UFD1-VCP complex regulates spindle disassembly at the end of mitosis and is necessary for the formation of a closed nuclear envelope. It may be involved in the development of some ectoderm-derived structures . Acts as a negative regulator of type I interferon production via the complex formed with VCP and NPLOC4, which binds to DDX58/RIG-I and recruits RNF125 to promote ubiquitination and degradation of DDX58/RIG-I (PubMed:26471729).

Specification

Entrez GeneID:7353

Swissprot:Q92890

WB Predicted band size:Calculated MW: 35 kDa; Observed MW: 40 kDa

Host/Isotype:Rabbit IgG

Antibody Type:Primary antibody

Storage:Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Species Reactivity:Human

免疫原:A synthetic peptide of human UFD1L

Formulation:Purified antibody in TBS with 0.05% sodium azide,0.05%BSA and 50% glycerol.

Application

Application:WB

WB:1/500-1/1000

宿主:Rabbit

商品参数

商品介绍
单位
品牌 ProMab/远泰

商品评论

暂无商品评论信息

商品咨询

暂无商品咨询信息

CONTENT