名称：NCAPH2

别名：CAPH2

描述

Regulatory subunit of the condensin-2 complex, a complex that seems to provide chromosomes with an additional level of organization and rigidity and in establishing mitotic chromosome architecture (PubMed:14532007). May promote the resolution of double-strand DNA catenanes (intertwines) between sister chromatids. Condensin-mediated compaction likely increases tension in catenated sister chromatids, providing directionality for type II topoisomerase-mediated strand exchanges toward chromatid decatenation. Required for decatenation of chromatin bridges at anaphase. Early in neurogenesis, may play an essential role to ensure accurate mitotic chromosome condensation in neuron stem cells, ultimately affecting neuron pool and cortex size . Seems to have lineage-specific role in T-cell development (PubMed:14532007).

Specification

Entrez GeneID：29781

Swissprot：Q6IBW4

WB Predicted band size：Calculated MW: 68 kDa; Observed MW: 68 kDa

Host/Isotype：Rabbit IgG

Antibody Type：Primary antibody

Storage：Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Species Reactivity：Human

免疫原：A synthetic peptide of human NCAPH2

Formulation：Purified antibody in TBS with 0.05% sodium azide,0.05%BSA and 50% glycerol.

Application

Application：WB,IP,IHC,IF

WB：1/500-1/1000

IP：1/10-1/20

IHC：1/50-1/100

ICC：1/50-1/200

宿主：Rabbit