名称：XIAP

别名：API3; ILP1; MIHA; XLP2; BIRC4; IAP-3; hIAP3; hIAP-3

描述

Multi-functional protein which regulates not only caspases and apoptosis, but also modulates inflammatory signaling and immunity, copper homeostasis, mitogenic kinase signaling, cell proliferation, as well as cell invasion and metastasis. Acts as a direct caspase inhibitor. Directly bind to the active site pocket of CASP3 and CASP7 and obstructs substrate entry. Inactivates CASP9 by keeping it in a monomeric, inactive state.

Specification

Entrez GeneID：11798

Swissprot：Q60989

WB Predicted band size：Calculated MW: 56 kDa; Observed MW: 53 kDa

Host/Isotype：Rabbit IgG

Antibody Type：Primary antibody

Storage：Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Species Reactivity：Human,Mouse,Rat

免疫原：Recombinant protein of mouse XIAP

Formulation：Purified antibody in TBS with 0.05% sodium azide,0.05%BSA and 50% glycerol.

Application

Application：WB

WB：1/500-1/1000

宿主：Rabbit