名称：CBFb

别名：CBFB; CBFbeta; PEA2; PEA2 beta; PEA2beta; PEBP2 beta; PEBP2B;;CBF beta

描述

Forms the heterodimeric complex core-binding factor (CBF) with RUNX family proteins (RUNX1, RUNX2, and RUNX3). RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'-TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.

Specification

Swissprot：Q13951

WB Predicted band size：22 kDa

Host/Isotype：Rabbit IgG

Antibody Type：Primary antibody

Storage：Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Species Reactivity：Human,Mouse,Rat

免疫原：A synthesized peptide derived from human CBF beta

Formulation：Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol.

Application

Application：WB,IHC/IHF,IF,FCM

WB：1/1000-1/2000

IHC：IHC:1/100-1/200;IHF:1/50-1/200

ICC：1/50-1/200

FCM：1/20-1/100

宿主：Rabbit