名称：HMGCR

别名：3H3M; HMDH; HMG CoA reductase; HMG CoAR;;HMGCR

描述

Catalyzes the conversion of (3S)-hydroxy-3-methylglutaryl-CoA (HMG-CoA) to mevalonic acid, the rate-limiting step in the synthesis of cholesterol and other isoprenoids, thus plays a critical role in cellular cholesterol homeostasis. HMGCR is the main target of statins, a class of cholesterol-lowering drugs.

Specification

Swissprot：P04035

WB Predicted band size：97 kDa

Host/Isotype：Rabbit IgG

Antibody Type：Primary antibody

Storage：Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Species Reactivity：Human,Mouse,Rat

免疫原：A synthesized peptide derived from human HMGCR

Formulation：Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol.

Application

Application：WB;IP

WB：1/1000-1/2000

IP：1/20-1/50

宿主：Rabbit