名称：PPP2R1A

别名：MRD36; PP2AA; PR65A; PP2AAALPHA; PP2A-Aalpha

Pathway：TGF-beta signaling pathway

Pathway：PI3K-Akt signaling pathway

Targets：Disease

描述

This gene encodes a constant regulatory subunit of protein phosphatase 2. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The constant regulatory subunit A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. This gene encodes an alpha isoform of the constant regulatory subunit A. Alternatively spliced transcript variants have been described.

Specification

Swissprot：P30153

Gene Accession：BC001537

WB Predicted band size：65 kDa

Host/Isotype：Rabbit IgG

Antibody Type：Primary antibody

Storage：Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Species Reactivity：Human, Mouse

免疫原：Fusion protein of human PPP2R1A

Formulation：Purified antibody in PBS with 0.05% sodium azide and 50% glycerol.

Application

Application：WB,IHC

WB：1/1000-1/5000

IHC：1/70-1/350

ELISA：1/5000-1/10000

宿主：Rabbit