名称：Neuropilin 1

别名：NRP1;NRP;VEGF165R;Neuropilin-1;Vascular endothelial cell growth factor 165 receptor;CD antigen CD304

Targets：Neuropilin

描述

This gene encodes one of two neuropilins, which contain specific protein domains which allow them to participate in several different types of signaling pathways that control cell migration. Neuropilins contain a large N-terminal extracellular domain, made up of complement-binding, coagulation factor V/VIII, and meprin domains. These proteins also contains a short membrane-spanning domain and a small cytoplasmic domain. Neuropilins bind many ligands and various types of co-receptors; they affect cell survival, migration, and attraction. Some of the ligands and co-receptors bound by neuropilins are vascular endothelial growth factor (VEGF) and semaphorin family members. Several alternatively spliced transcript variants that encode different protein isoforms have been described for this gene. [provided by RefSeq, Oct 2011],

Specification

Entrez GeneID：8829

Swissprot：O14786

WB Predicted band size：103kD

Host/Isotype：Rabbit IgG,Kappa

Antibody Type：Primary antibody

Storage：-15°C to -25°C/1 year(Do not lower than -25°C)

Species Reactivity：Human,Mouse,Rat,

Formulation：PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Application

Application：WB,IHC,IF,IP,ELISA

WB：1/1000-5000

IP：1/50-200

IHC：1/200-1000

ICC：1/200-1000

ELISA：1/5000-20000

宿主：Rabbit