名称：NGFR

别名：CD271; p75NTR; TNFRSF16; p75(NTR); Gp80-LNGFR

Pathway：TGF-beta signaling pathway

Pathway：PI3K-Akt signaling pathway

Pathway：Hippo signaling pathway

描述

Nerve growth factor receptor contains an extracellular domain containing four 40-amino acid repeats with 6 cysteine residues at conserved positions followed by a serine/threonine-rich region, a single transmembrane domain, and a 155-amino acid cytoplasmic domain. The cysteine-rich region contains the nerve growth factor binding domain.

文献

1.Math Biosci Eng. 2019 Sep 5;16(6):8060-8068.
2.Sci Rep. 2019 May 22;9(1):7696.

Specification

Entrez GeneID：4804

Swissprot：P08138

clone：8G8H10

WB Predicted band size：45.2kDa

Host/Isotype：Mouse IgG1

Antibody Type：Primary antibody

Storage：Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Species Reactivity：Human

免疫原：Purified recombinant fragment of human NGFR (AA: 1-200 ) expressed in E. Coli.

Formulation：Purified antibody in PBS with 0.05% sodium azide

Application

Application：IHC,FCM

IHC：1/200 - 1/1000

FCM：1/200 - 1/400

ELISA：1/10000

宿主：Mouse