名称：alpha Tubulin

别名：ALS22; TUBA1; H2-ALPHA;Alpha-tubulin 1;TBA4A;α Tubulin

Targets：FDA approved drug target related

描述

Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulin. The genes encoding these microtubule constituents are part of the tubulin superfamily, which is composed of six distinct families. Genes from the alpha, beta and gamma tubulin families are found in all eukaryotes. The alpha and beta tubulins represent the major components of microtubules, while gamma tubulin plays a critical role in the nucleation of microtubule assembly. There are multiple alpha and beta tubulin genes and they are highly conserved among and between species. This gene encodes an alpha tubulin that is a highly conserved homolog of a rat testis-specific alpha tubulin. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2013]

文献

1,J Neurol Neurosurg Psychiatry. 2018 Dec;89(12):1350-1352.
2,Neurodegener Dis. 2017;17(4-5):171-180.

Specification

Entrez GeneID：7277

Swissprot：P68363/P68366

clone：1C4E12

WB Predicted band size：50kDa

Host/Isotype：Mouse IgG2a

Antibody Type：Loading Control Antibody

Storage：Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Species Reactivity：Human, Mouse, Rat, Monkey

免疫原：Purified recombinant fragment of human TUBA4A (AA: (299-447)) expressed in E. Coli.

Formulation：Purified antibody in PBS with 0.05% sodium azide

Application

Application：WB,IHC,FCM

WB：1/500 - 1/2000

IHC：1/200-1/1000

FCM：1/200-1/400

ELISA：1/10000

宿主：Mouse