名称：Fibrillarin

Targets：FBL

描述

This gene product is a component of a nucleolar small nuclear ribonucleoprotein (snRNP) particle thought to participate in the first step in processing preribosomal RNA. It is associated with the U3, U8, and U13 small nuclear RNAs and is located in the dense fibrillar component (DFC) of the nucleolus. The encoded protein contains an N-terminal repetitive domain that is rich in glycine and arginine residues, like fibrillarins in other species. Its central region resembles an RNA-binding domain and contains an RNP consensus sequence. Antisera from approximately 8% of humans with the autoimmune disease scleroderma recognize fibrillarin. [provided by RefSeq, Jul 2008]

Specification

Entrez GeneID：2091

Swissprot：P22087

WB Predicted band size：34kD

Host/Isotype：Rabbit IgG,Kappa

Antibody Type：Primary antibody

Storage：-15°C to -25°C/1 year(Do not lower than -25°C)

Species Reactivity：Human,Mouse,Rat,

Formulation：PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Application

Application：WB,IHC,IF,IP,ELISA

WB：1/1000-5000

IP：1/50-200

IHC：1/200-1000

ICC：1/200-1000

ELISA：1/5000-20000

宿主：Rabbit