名称：NDC80

别名：HEC; HEC1; TID3; KNTC2; HsHec1; hsNDC80

描述

This gene encodes a component of the NDC80 kinetochore complex. The encoded protein consists of an N-terminal microtubule binding domain and a C-terminal coiled-coiled domain that interacts with other components of the complex. This protein functions to organize and stabilize microtubule-kinetochore interactions and is required for proper chromosome segregation. [provided by RefSeq, Oct 2011]

文献

1.J Biol Chem.2019 Jan 11;294(2):576-592.
2.Mol Biol Cell.2020 Jul 1;31(14):1453-1473.

Specification

Entrez GeneID：10403

Swissprot：O14777

clone：4B12H3

WB Predicted band size：74kDa

Host/Isotype：Mouse IgG1

Antibody Type：Primary antibody

Storage：Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Species Reactivity：Human

免疫原：Purified recombinant fragment of human NDC80 (AA: 443-642) expressed in Mammalian.

Formulation：Purified antibody in PBS with 0.05% sodium azide

Application

Application：WB,IHC,FCM

WB：1/500 - 1/2000

IHC：1/200 - 1/1000

FCM：1/200 - 1/400

ELISA：1/10000

宿主：Mouse