名称：TTF1

别名：TTF-1; TTF-I

描述

This gene encodes a transcription termination factor that is localized to the nucleolus and plays a critical role in ribosomal gene transcription. The encoded protein mediates the termination of RNA polymerase I transcription by binding to Sal box terminator elements downstream of pre-rRNA coding regions. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. This gene shares the symbol/alias 'TFF1' with another gene, NK2 homeobox 1, also known as thyroid transcription factor 1, which plays a role in the regulation of thyroid-specific gene expression.

文献

1.Tumour Biol. 2015 Sep;36(10):8085-92.
2.Chest. 2013 Oct;144(4):1199-206.

Specification

Entrez GeneID：7270

Swissprot：Q15361

clone：2F4B12

WB Predicted band size：103kDa

Host/Isotype：Mouse IgG1

Antibody Type：Primary antibody

Storage：Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Species Reactivity：Human

免疫原：Purified recombinant fragment of human TTF1 (AA: 1-150) expressed in E. Coli.

Formulation：Purified antibody in PBS with 0.05% sodium azide

Application

Application：FCM

FCM：1/200 - 1/400

ELISA：1/10000

宿主：Mouse