名称：KAT2B

别名：CAF; PCAF; P/CAF

Targets：Disease

描述

CBP and p300 are large nuclear proteins that bind to many sequence-specific factors involved in cell growth and/or differentiation, including c-jun and the adenoviral oncoprotein E1A. The protein encoded by this gene associates with p300/CBP. It has in vitro and in vivo binding activity with CBP and p300, and competes with E1A for binding sites in p300/CBP. It has histone acetyl transferase activity with core histones and nucleosome core particles, indicating that this protein plays a direct role in transcriptional regulation.

文献

1.Cell Death Dis. 2016 Oct 6;7(10):e2400.
2.J Biol Chem. 2016 Jul 1;291(27):14363-72.

Specification

Entrez GeneID：8850

Swissprot：Q92831

clone：7D12C8

WB Predicted band size：93kDa

Host/Isotype：Mouse IgG1

Antibody Type：Primary antibody

Storage：Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Species Reactivity：Human,Mouse,Rat,Monkey

免疫原：Purified recombinant fragment of human KAT2B (AA: 1-142) expressed in E. Coli.

Formulation：Purified antibody in PBS with 0.05% sodium azide

Application

Application：WB,IHC,IF,FCM

IHC：1/200 - 1/1000

ICC：1/200 - 1/1000

FCM：1/200 - 1/400

ELISA：1/10000

宿主：Mouse