名称：CBX8

别名：PC3; RC1

描述

Chromobox homolog 8 (CBX8), a Polycomb Group protein that interacts with MLL-AF9 and TIP60, plays an essential role in MLL-AF9 transcriptional regulation and leukemogenesis. CBX8, which is part of one of the PRC1 complexes, regulates proliferation of diploid human and mouse fibroblasts through direct binding to the INK4A-ARF locus.

文献

1.Cancer Cell. 2011 Nov 15;20(5):563-75.
2.EMBO J. 2007 Mar 21;26(6):1637-48.

Specification

Entrez GeneID：57332

Swissprot：Q9HC52

clone：9C3D4

WB Predicted band size：43.4kDa

Host/Isotype：Mouse IgG1

Antibody Type：Primary antibody

Storage：Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Species Reactivity：Human

免疫原：Purified recombinant fragment of human CBX8 (AA: 17-222) expressed in E. Coli.

Formulation：Purified antibody in PBS with 0.05% sodium azide

Application

Application：WB,FCM

WB：1/500 - 1/2000

FCM：1/200 - 1/400

ELISA：1/10000

宿主：Mouse