名称：ACTA2

别名：AAT6; ACTSA; α-Smooth Muscle Actin;Alpha-actin-2;Alpha actin 2

Targets：Disease

描述

The protein encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Defects in this gene cause aortic aneurysm familial thoracic type 6. Multiple alternatively spliced variants, encoding the same protein, have been identified.

文献

1. J Hum Genet. 2009 Nov;54(11):687-8.
2. Hum Mutat. 2009 Oct;30(10):1406-11.

Specification

Entrez GeneID：59

Swissprot：P62736

clone：4A4

WB Predicted band size：42kDa

Host/Isotype：Mouse IgG1

Antibody Type：Primary antibody

Storage：Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Species Reactivity：Human,Mouse,Rat,Monkey

免疫原：Synthesized peptide of human ACTA2.

Formulation：Ascitic fluid containing 0.03% sodium azide.

Application

Application：WB,IHC,IF,FCM

WB：1/500 - 1/2000

IHC：1/200 - 1/500

ICC：1/50- 1/500

FCM：1/200 - 1/400

ELISA：1/10000

宿主：Mouse