名称：CEBPA

别名：CEBP; C/EBP-alpha

Targets：Disease

描述

The protein encoded by this intronless gene is a bZIP transcription factor which can bind as a homodimer to certain promoters and enhancers. It can also form heterodimers with the related proteins CEBP-beta and CEBP-gamma. The encoded protein has been shown to bind to the promoter and modulate the expression of the gene encoding leptin, a protein that plays an important role in body weight homeostasis. Also, the encoded protein can interact with CDK2 and CDK4, thereby inhibiting these kinases and causing growth arrest in cultured cells.

文献

Br J Cancer. 2010 Jul 13;103(2):275-84.
Cell Res. 2010 Apr;20(4):470-9.

Specification

Entrez GeneID：1050

Swissprot：P49715

clone：5B7

WB Predicted band size：42kDa

Host/Isotype：Mouse IgG1

Antibody Type：Primary antibody

Storage：Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Species Reactivity：Human

免疫原：Synthesized peptide of human CEBPA (AA: C-RKSRDKAKRNVETKV).

Formulation：Purified antibody in PBS with 0.05% sodium azide.

Application

Application：WB,IHC,IF,FCM

WB：1/500 - 1/2000

IHC：1/200 - 1/1000

ICC：1/200 - 1/1000

FCM：1/200 - 1/400

ELISA：1/10000

宿主：Mouse