名称：HSP60

别名：HLD4; CPN60; GROEL; HSP60; HSP65; SPG13; HSP-60; HuCHA60; HSPD1

Targets：Disease

描述

This gene encodes a member of the chaperonin family. The encoded mitochondrial protein may function as a signaling molecule in the innate immune system. This protein is essential for the folding and assembly of newly imported proteins in the mitochondria. This gene is adjacent to a related family member and the region between the 2 genes functions as a bidirectional promoter. Several pseudogenes have been associated with this gene. Two transcript variants encoding the same protein have been identified for this gene. Mutations associated with this gene cause autosomal recessive spastic paraplegia 13. (provided by RefSeq)

文献

1. Clin Exp Rheumatol. 2008 Nov-Dec;26(6):1107-10.
2. APMIS. 2008 Oct;116(10):888-95.

Specification

Entrez GeneID：3329

Swissprot：P10809

clone：3G8

WB Predicted band size：61kDa

Host/Isotype：Mouse IgG1

Antibody Type：Loading Control Antibody

Storage：Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Species Reactivity：Human,Mouse,Rat,Monkey

免疫原：Purified recombinant fragment of human HSP60 expressed in E. Coli.

Formulation：Purifed antibody in PBS with 0.05% sodium azide.

Application

Application：WB,IHC,IF,FCM

WB：1/500 - 1/2000

IHC：1/200 - 1/1000

ICC：1/200 - 1/1000

FCM：1/200 - 1/400

ELISA：1/10000

宿主：Mouse