名称：SRC

别名：ASV; SRC1; c-SRC; p60-Src

Pathway：Jak-STAT signaling pathway

Targets：Disease

描述

SRC: v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian). This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene.

文献

1. Pancreas. 2005 Oct;31(3):263-74.
2. Clin Exp Metastasis. 2005;22(3):195-204.
3. J Mol Biol. 2005 Oct 21;353(2):222-31.

Specification

Entrez GeneID：6714

Swissprot：P12931

clone：5D10C4

Host/Isotype：Mouse IgG2a

Antibody Type：Primary antibody

Storage：Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Species Reactivity：Human

免疫原：Purified recombinant fragment of SRC (aa10-193) expressed in E. Coli.

Formulation：Ascitic fluid containing 0.03% sodium azide.

Application

Application：ELISA

WB：1/500 - 1/2000

ELISA：1/10000

宿主：Mouse