名称：SND1/P100

别名：p100; TDRD11; TudorSN

描述

SND1/P100 (staphylococcal nuclease and tudor domain containing 1), also known as TudorSN, it functions in the Pim-1 regulation of Myb activity and acts as a transcriptional activatior of EBNA-2. It also interacts with EAV, NSP1,GTF2E1 and GTF2E2, and forms a ternary complex with Stat6 and POLR2A. The staphylococcal nuclease-like (SN)-domains directly interact with amino acids 1099-1758 of CBP. SND1/P100 plays an important role in the assembly of Stat6 transcriptome and stimulates IL-4-dependent transcription by mediating interaction between Stat6 and CBP.

文献

1. J Gen Virol. 2003 Sep;84(Pt 9):2317-22.
2. Biochim Biophys Acta. 2005 Jan 11;1681(2-3):126-33.

Specification

Entrez GeneID：27044

Swissprot：Q7KZF4

clone：2D7

WB Predicted band size：102kDa

Host/Isotype：Mouse IgG1

Antibody Type：Primary antibody

Storage：Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Species Reactivity：Human

免疫原：Purified recombinant fragment of SND1 (aa361-485) expressed in E. Coli.

Formulation：Purifed antibody in PBS with 0.05% sodium azide.

Application

Application：WB

WB：1/500 - 1/2000

ELISA：1/10000

宿主：Mouse