靶标 LMTK3 别名 BC059845; KIAA1883; Lemur tyrosine kinase 3; LMR3; MGC90743; Serine/threonine-protein kinase LMTK3; TYKLM3 宿主 Rabbit 稀释比例 IHC 1:50-200. Gene ID 114783 保存 Store at -20℃. Avoid freeze / thaw cycles. Swiss Prot Q96Q04 蛋白分子量 153kDa 储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. 亚细胞定位 Nucleus Cytoplasm Cell membrane 免疫原 A synthetic peptide of Human LMTK3 亚型 IgG 纯化方法 Affinity purification 背景资料 Protein kinase which phosphorylates ESR1 (in vitro) and protects it against proteasomal degradation. May also regulate ESR1 levels indirectly via a PKC-AKT-FOXO3 pathway where it decreases the activity of PKC and the phosphorylation of AKT, thereby increasing binding of transcriptional activator FOXO3 to the ESR1 promoter and increasing ESR1 transcription (PubMed:21602804). Involved in endocytic trafficking of N-methyl-D-aspartate receptors (NMDAR) in neurons (By similarity). Public Immunogen Range 265-315/1406aa 克隆类型 Polyclonal Antibody 交叉反应 Human;Mouse 应用 IHC 规格 50ul 100ul