英文名称 Anti-GAPDH Polyclonal Antibody 别名 GAPD;CDABP0047;OK/SW-cl.12;G3PD;HEL-S-162eP 宿主 Rabbit 稀释比例 WB 1:5000. Gene ID 2597 保存 Store at -20°C. Avoid freeze / thaw cycles. Swiss Prot P04406 蛋白分子量 36kDa 储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. 亚细胞定位 Cytoplasm Membrane Nucleus cytoskeleton cytosol perinuclear region 免疫原 Recombinant protein of human GAPDH 亚型 IgG 性状 液体 纯化方法 Affinity purification 背景资料 Glyceraldehyde 3 phosphate dehydrogenase (GAPDH) is well known as one of the key enzymes involved in glycolysis. As well as functioning as a glycolytic enzyme in cytoplasm, recent evidence suggests that mammalian GAPDH is also involved in a great number of intracellular proceses such as membrane fusion, microtubule bundling, phosphotransferase activity, nuclear RNA export, DNA replication, and DNA repair. During the last decade a lot of data appeared concerning the role of GAPDH in different pathologies including prostate cancer progression, programmed neuronal cell death, age related neuronal diseases, such as Alzheimer's and Huntington's disease. GAPDH is expressed in all cells. It is constitutively expressed in almost all tissues at high levels. There are however some physiological factors such as hypoxia and diabetes that increase GAPDH expression in certain cell types. GAPDH molecule is composed of four 36kDa subunits. Public Immunogen Range 1-333aa 克隆类型 Polyclonal Antibody 交叉反应 Human Rat Mouse 应用 WB 规格 50ul 100ul 使用前请离心。如有问题请及时联系我们。