英文名称 Anti-PARP Monoclonal Antibody 别名 ADPRT;ADPRT1;ADPRT1;ARTD1;pADPRT-1;PARP;PARP-1;PPOL 宿主 Mouse 稀释比例 WB 1:1000-3000. IHC 1:200-500. Gene ID 142 保存 Store at -20°C. Avoid freeze / thaw cycles. Swiss Prot P09874 储存液 Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. 蛋白分子量 116/89kDa 亚细胞定位 Nucleus nucleolus 免疫原 Synthetic Peptide 亚型 IgG1 性状 液体 纯化方法 Saturated ammonium sulfate precipitation 克隆号 M3 背景资料 Poly [ADP-ribose] polymerase 1 (PARP-1) also known as NAD+ ADP-ribosyltransferase 1 or poly[ADP-ribose] synthase 1 is an enzyme that in humans is encoded by the PARP1 gene. PARP1 has a role in repair of single-stranded DNA (ssDNA) breaks. Knocking down intracellular PARP1 levels with siRNA or inhibiting PARP1 activity with small molecules reduces repair of ssDNA breaks. In the absence of PARP1, when these breaks are encountered during DNA replication, the replication fork stalls, and double-strand DNA (dsDNA) breaks accumulate. Public Immunogen Range Synthetic Peptide 克隆类型 Monoclonal Antibody 交叉反应 Human 应用 WB IHC 规格 50ul 100ul 使用前请离心。如有问题请及时联系我们。