英文名称 Anti-CDH2 Polyclonal Antibody 靶标 CDH2 别名 Cadherin-2;CDw325;Neural cadherin;N-cadherin;CD325;CDHN;NCAD 宿主 Rabbit 预测交叉反应 Cow;Chimpanzee;Chicken;Monkey 稀释比例 WB 1:1000-3000. Gene ID 1000 保存 Store at -20°C. Avoid freeze / thaw cycles. Swiss Prot P19022 蛋白分子量 97/100kDa 储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. 亚细胞定位 Cell membrane 免疫原 A synthetic peptide of human CDH2 亚型 IgG 纯化方法 Affinity purification 背景资料 Calcium-dependent cell adhesion protein; preferentially mediates homotypic cell-cell adhesion by dimerization with a CDH2 chain from another cell. Cadherins may thus contribute to the sorting of heterogeneous cell types. Acts as a regulator of neural stem cells quiescence by mediating anchorage of neural stem cells to ependymocytes in the adult subependymal zone: upon cleavage by MMP24, CDH2-mediated anchorage is affected, leading to modulate neural stem cell quiescence. Plays a role in cell-to-cell junction formation between pancreatic beta cells and neural crest stem (NCS) cells, promoting the formation of processes by NCS cells (By similarity). CDH2 may be involved in neuronal recognition mechanism. In hippocampal neurons, may regulate dendritic spine density. Public Immunogen Range 800-850/906aa 克隆类型 Polyclonal Antibody 应用 WB 规格 50ul 100ul 使用前请离心。如有问题请及时联系我们。