靶标 ARHGEF11 别名 ARHGB_HUMAN; ARHGEF 11; ARHGEF11; DKFZp667F1223; Glutamate transporter EAAT4 associated protein 48; GTRAP 48; GTRAP48; KIAA0380; OTTHUMP00000038716; OTTHUMP00000038717; PDZ RHOGEF; PDZ-RhoGEF; Rho guanine exchange factor (GEF) 11; Rho guanine nucleotide exchange factor (GEF) 11; Rho guanine nucleotide exchange factor 11; RhoA specific guanine nucleotide exchange factor; RhoGEF glutamate transport modulator 宿主 Rabbit 稀释比例 IHC 1:50-200. Gene ID 9826 保存 Store at -20℃. Avoid freeze / thaw cycles. Swiss Prot O15085 蛋白分子量 167/172kDa 储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. 亚细胞定位 Cytoplasm 免疫原 A synthetic peptide of Human ARHGEF11 亚型 IgG 纯化方法 Octanoic acid-ammonium sulfate precipitation 背景资料 Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. A similar protein in rat interacts with glutamate transporter EAAT4 and modulates its glutamate transport activity. Expression of the rat protein induces the reorganization of the actin cytoskeleton and its overexpression induces the formation of membrane ruffling and filopodia. Two alternative transcripts encoding different isoforms have been described. Public Immunogen Range 435-485/1522aa 克隆类型 Polyclonal Antibody 交叉反应 Human;Rat 应用 IHC 规格 50ul 100ul