实际分子量 59kDa 靶标 PTBP1 别名 57 kDa RNA binding protein PPTB 1; 57 kDa RNA-binding protein PPTB-1; Heterogeneous nuclear ribonucleoprotein I; Heterogeneous Nuclear Ribonucleoprotein Polypeptide I; hnRNP I; HNRNP-I; HNRNPI; HNRPI; MGC10830; MGC8461 宿主 Rabbit 预测交叉反应 Bovine;Pig 稀释比例 WB 1:1000-3000. Gene ID 5725 保存 Store at -20℃. Avoid freeze / thaw cycles. Swiss Prot P26599 蛋白分子量 57/59kDa 储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. 亚细胞定位 Nucleus 免疫原 Recombinant protein of human PTBP1 亚型 IgG 纯化方法 Octanoic acid-ammonium sulfate precipitation 背景资料 This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA-binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has four repeats of quasi-RNA recognition motif (RRM) domains that bind RNAs. This protein binds to the intronic polypyrimidine tracts that requires pre-mRNA splicing and acts via the protein degradation ubiquitin-proteasome pathway. It may also promote the binding of U2 snRNP to pre-mRNAs. This protein is localized in the nucleoplasm and it is also detected in the perinucleolar structure. Alternatively spliced transcript variants encoding different isoforms have been described. Public Immunogen Range 1-350aa 克隆类型 Polyclonal Antibody 交叉反应 Human;Mouse;Rat 应用 WB 规格 50ul 100ul