英文名称 Anti-LMNA Monoclonal Antibody 别名 CDCD1;CDDC;CMD1A;CMT2B1;EMD2;FPL;FPLD;FPLD2;HGPS;IDC;LDP1;LFP;LGMD1B;LMN1;LMNC;LMNL1;MADA;PRO1;Lamin A/C 宿主 Mouse 稀释比例 WB 1:1000. ICC 1:200. Gene ID 4000 保存 Store at -20°C. Avoid freeze / thaw cycles. Swiss Prot P02545 储存液 Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. 蛋白分子量 74/65/71/64/63/69kDa 亚细胞定位 Nucleus Nucleus envelope Nucleus lamina Nucleus speckle nucleoplasm 免疫原 Purified recombinant human LMNA protein fragments expressed in E.coli. 亚型 IgG1 性状 液体 纯化方法 Affinity purification 克隆号 5D12-C6-E9 背景资料 The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. Alternative splicing results in multiple transcript variants. Mutations in this gene lead to several diseases: Emery-Dreifuss muscular dystrophy, familial partial lipodystrophy, limb girdle muscular dystrophy, dilated cardiomyopathy, Charcot-Marie-Tooth disease, and Hutchinson-Gilford progeria syndrome. Public Immunogen Range Purified recombinant human LMNA protein fragments expressed in E.coli. 克隆类型 Monoclonal Antibody 交叉反应 Human 应用 WB IF 规格 50ul 100ul 使用前请离心。如有问题请及时联系我们。