英文名称 Anti-CAV1 Polyclonal Antibody 别名 BSCL3;CGL3;LCCNS;MSTP085;PPH3;VIP21;Caveolin-1;CAV; 宿主 Rabbit 稀释比例 WB 1:1000-3000. Gene ID 857 保存 Store at -20°C. Avoid freeze / thaw cycles. Swiss Prot Q03135 蛋白分子量 17/20kDa 储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. 亚细胞定位 Cell membrane Cytoplasm 免疫原 Recombinant protein of human CAV1 亚型 IgG 纯化方法 Affinity purification 背景资料 The scaffolding protein encoded by this gene is the main component of the caveolae plasma membranes found in most cell types. The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. The gene is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 mitogen-activated kinase cascade. Caveolin 1 and caveolin 2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. Mutations in this gene have been associated with Berardinelli-Seip congenital lipodystrophy. Alternatively spliced transcripts encode alpha and beta isoforms of caveolin 1. Public Immunogen Range 1-178aa 克隆类型 Polyclonal Antibody 交叉反应 Human Rat Mouse 应用 WB 规格 50ul 100ul 使用前请离心。如有问题请及时联系我们。