靶标 ZNF281 别名 ZBP-99; ZNP-99 宿主 Rabbit 稀释比例 WB 1:500-2000. IHC 1:60-450 Gene ID 23528 保存 Store at -20°C. Avoid freeze / thaw cycles. Swiss Prot Q9Y2X9 蛋白分子量 97 kDa 储存液 pH7.4 PBS, 0.05% NaN3, 40% Glycerol 亚细胞定位 Cytoplasm Nucleus 免疫原 Fusion protein of human ZNF281 亚型 IgG 纯化方法 Antigen affinity purification 背景资料 Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. ZNF281, also known as GC-box-binding zinc finger protein 1, ZBP-99 or ZNP-99 (zinc finger DNA-binding protein 99), is a zinc finger protein that belongs to the Krüppel C2H2-type zinc finger protein family. It is expressed ubiquitously at low levels with predominant expression in kidney, liver, lymphocytes and placenta. ZNF281 localizes to the nucleus and contains four C2H2-type zinc fingers. ZNF281 plays a role in repressing the transcription of a variety of genes including Gastrin and ODC (ornithine decarboxylase). In particular, ZNF281 functions by binding to the G-rich box in the enhancer region of the gene. Upon DNA damage, ZNF281 may become phosphorylated by Atm or ATR. 克隆类型 Polyclonal Antibody 交叉反应 Human Mouse 应用 WB ELISA IHC 规格 50ul 100ul 使用前请离心。如有问题请及时联系我们。