靶标 MRTFA 别名 AI852829; AMKL; AW743281; AW821984; Basic SAP coiled-coil transcription activator; Bsac; KIAA1438; Mal; Megakaryoblastic leukemia 1 protein; Megakaryocytic acute leukemia protein; MKL (megakaryoblastic leukemia)/myocardin like 1; MKL/myocardin like protein 1; MKL/myocardin-like protein 1; Mkl1; MKL1_HUMAN; MRTF A; Mrtf A; MRTF-A; MRTFA; MYOCARDIN RELATED PROTEIN; Myocardin related transcription factor A; Myocardin-related transcription factor A; 宿主 Rabbit 稀释比例 WB 1:1000-3000. Gene ID 57591 保存 Store at -20°C. Avoid freeze / thaw cycles. Swiss Prot Q969V6 蛋白分子量 99kDa 储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. 亚细胞定位 Cytoplasm Nucleus 免疫原 A synthetic peptide of human MRTFA 亚型 IgG 纯化方法 Octanoic acid-ammonium sulfate precipitation 背景资料 Transcription coactivator that associates with the serum response factor (SRF) transcription factor to control expression of genes regulating the cytoskeleton during development, morphogenesis and cell migration. The SRF-MRTFA complex activity responds to Rho GTPase-induced changes in cellular globular actin (G-actin) concentration, thereby coupling cytoskeletal gene expression to cytoskeletal dynamics. MRTFA binds G-actin via its RPEL repeats, regulating activity of the MRTFA-SRF complex. Activity is also regulated by filamentous actin (F-actin) in the nucleus. Public Immunogen Range 755-805/931 克隆类型 Polyclonal Antibody 交叉反应 Human Mouse 应用 WB 规格 50ul 100ul 使用前请离心。如有问题请及时联系我们。