靶标 E2F6 别名 E2F-6 宿主 Rabbit 稀释比例 WB 1:1000-3000. Gene ID 1876 保存 Store at -20°C. Avoid freeze / thaw cycles. Swiss Prot O75461 蛋白分子量 23/28/32kDa 储存液 Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. 亚细胞定位 Nucleus 免疫原 Recombinant protein of human E2F6 亚型 IgG 纯化方法 Octanoic acid-ammonium sulfate precipitation 背景资料 Inhibitor of E2F-dependent transcription. Binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3'. Has a preference for the 5'-TTTCCCGC-3' E2F recognition site. E2F6 lacks the transcriptional activation and pocket protein binding domains. Appears to regulate a subset of E2F-dependent genes whose products are required for entry into the cell cycle but not for normal cell cycle progression. May silence expression via the recruitment of a chromatin remodeling complex containing histone H3-K9 methyltransferase activity. Overexpression delays the exit of cells from the S-phase. Public Immunogen Range 1-282aa 克隆类型 Polyclonal Antibody 交叉反应 Human Rat Mouse 应用 WB 规格 50ul 100ul 使用前请离心。如有问题请及时联系我们。