英文名称 Anti-INDO Polyclonal Antibody 靶标 PISD 别名 IDO;IDO-1;INDO;indoleamine 2 宿主 Rabbit 稀释比例 WB 1:1000-3000. Gene ID 3620 保存 Store at -20°C. Avoid freeze / thaw cycles. Swiss Prot P14902 蛋白分子量 45kDa 储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. 亚细胞定位 Cytoplasm 免疫原 Recombinant protein of human INDO 亚型 IgG 纯化方法 Affinity purification 背景资料 Catalyzes the first and rate limiting step of the catabolism of the essential amino acid tryptophan along the kynurenine pathway (PubMed:17671174). Involved in the peripheral immune tolerance, contributing to maintain homeostasis by preventing autoimmunity or immunopathology that would result from uncontrolled and overreacting immune responses (PubMed:25691885). Tryptophan shortage inhibits T lymphocytes division and accumulation of tryptophan catabolites induces T-cell apoptosis and differentiation of regulatory T-cells. Acts as a suppressor of anti-tumor immunity. Limits the growth of intracellular pathogens by depriving tryptophan. Protects the fetus from maternal immune rejection. Public Immunogen Range 61-404aa 克隆类型 Polyclonal Antibody 交叉反应 Human Rat Mouse 应用 WB 规格 50ul 100ul 使用前请离心。如有问题请及时联系我们。