英文名称 Anti-UCP1 Polyclonal Antibody 别名 SLC25A7;Thermogenin;UCP;UCP1;UCP1 宿主 Rabbit 稀释比例 WB 1:500-1000. IHC 1:20-200. Gene ID 7350 保存 Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. Swiss Prot P25874 蛋白分子量 33kDa 储存液 PBS with 0.02% sodium azide and 50% glycerol pH 7.3. 亚细胞定位 Membrane Mitochondrion Mitochondrion inner membrane 免疫原 Recombinant fusion protein of Human UCP1 亚型 IgG 纯化方法 Affinity purification 背景资料 Mitochondrial protein responsible for thermogenic respiration, a specialized capacity of brown adipose tissue and beige fat that participates in non-shivering adaptive thermogenesis to temperature and diet variations and more generally to the regulation of energy balance (By similarity). Functions as a long-chain fatty acid/LCFA and proton symporter, simultaneously transporting one LCFA and one proton through the inner mitochondrial membrane (PubMed:24196960). However, LCFAs remaining associated with the transporter via their hydrophobic tails, it results in an apparent transport of protons activated by LCFAs. Thereby, dissipates the mitochondrial proton gradient and converts the energy of substrate oxydation into heat instead of ATP. Regulates the production of reactive oxygen species/ROS by mitochondria (By similarity). 克隆类型 Polyclonal Antibody 交叉反应 Human Rat Mouse 应用 IHC ELISA WB 规格 50ul 100ul 使用前请离心。如有问题请及时联系我们。