英文名称 Anti-TIRAP Polyclonal Antibody 靶标 KLHL6 别名 BACTS1; Mal; MyD88-2; wyatt; TIR domain containing adaptor protein 宿主 Rabbit 稀释比例 IHC 1:100-300. Gene ID 114609 保存 Store at -20°C. Avoid freeze / thaw cycles. Swiss Prot P58753 蛋白分子量 24/25/28kDa 储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. 亚细胞定位 Cell membrane Cytoplasm 免疫原 A synthetic peptide of TIRAP 亚型 IgG 纯化方法 Affinity purification 背景资料 The innate immune system recognizes microbial pathogens through Toll-like receptors (TLRs), which identify pathogen-associated molecular patterns. Different TLRs recognize different pathogen-associated molecular patterns and all TLRs have a Toll-interleukin 1 receptor (TIR) domain, which is responsible for signal transduction. The protein encoded by this gene is a TIR adaptor protein involved in the TLR4 signaling pathway of the immune system. It activates NF-kappa-B, MAPK1, MAPK3 and JNK, which then results in cytokine secretion and the inflammatory response. Alternative splicing of this gene results in several transcript variants; however, not all variants have been fully described. Public Immunogen Range 171-221/221aa 克隆类型 Polyclonal Antibody 交叉反应 Human Rat Mouse 应用 IHC 规格 50ul 100ul 使用前请离心。如有问题请及时联系我们。