靶标 CAPN6 别名 CANPX; CAPNX; CalpM; DJ914P14.1 宿主 Rabbit 稀释比例 WB 1:500-2000. IHC 1:50-100 Gene ID 827 保存 Store at -20°C. Avoid freeze / thaw cycles. Swiss Prot Q9Y6Q1 蛋白分子量 75 kDa 储存液 pH7.4 PBS, 0.05% NaN3, 40% Glycerol 亚细胞定位 Cytoplasm 免疫原 Fusion protein of human CAPN6 亚型 IgG 纯化方法 Antigen affinity purification 背景资料 Calpains are ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large subunit possesses a cysteine protease domain, and both subunits possess calcium-binding domains. Calpains have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. The protein encoded by this gene is highly expressed in the placenta. Its C-terminal region lacks any homology to the calmodulin-like domain of other calpains. The protein lacks critical active site residues and thus is suggested to be proteolytically inactive. The protein may play a role in tumor formation by inhibiting apoptosis and promoting angiogenesis. 克隆类型 Polyclonal Antibody 交叉反应 Human Rat Mouse 应用 WB ELISA IHC 规格 50ul 100ul 使用前请离心。如有问题请及时联系我们。