英文名称 Anti-CBX6 Polyclonal Antibody 别名 Cbx 6; Cbx6; CBX6_HUMAN; Chromobox homolog 6; Chromobox protein homolog 6; 宿主 Rabbit 稀释比例 WB 1:1000-3000. Gene ID 23466 保存 Store at -20°C. Avoid freeze / thaw cycles. Swiss Prot O95503 蛋白分子量 44kDa 储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. 亚细胞定位 Cytoplasm Nucleus 免疫原 A synthetic peptide ofHuman CBX6 亚型 IgG 纯化方法 Affinity purification 背景资料 Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development (PubMed:21282530). PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. Possibly contributes to the target selectivity of the PRC1 complex by binding specific regions of chromatin (PubMed:18927235). Recruitment to chromatin might occur in an H3K27me3-independent fashion (By similarity). May have a PRC1-independent function in embryonic stem cells (By similarity). Public Immunogen Range 335-385/412aa 克隆类型 Polyclonal Antibody 交叉反应 Human Mouse 应用 WB 规格 50ul 100ul 使用前请离心。如有问题请及时联系我们。